This mysterious protein punctures our cells-now researchers know how
• The human body is a dynamic place • Blood pumps, spinal fluid flows, oxygen comes in and carbon dioxide goes out • Deeper still, charged molecules pass through cell walls, quietl
Protein
Bacteria deliver a microtubule-binding protein into mammalian cells to promote colonization
• Science, Volume 391, Issue 6787, Page 825-830, February 2026. • Science, Volume 391, Issue 6787, Page 825-830, February 2026.
A flaw in using pretrained protein language models in protein-protein interaction inference models
• Abstract With the growing pervasiveness of pretrained protein language models (pLMs), pLM-based methods are increasingly being put forward for the protein-protein interaction (PP
Electrochemical signals can reshape bacterial protein patterns, boosting electron transfer
• Sometimes, transporting electrons from one cell to another is a team effort. • In electroactive bacteria, that team is a group of proteins that shepherds electrons forward, passi
Bacteria deliver a microtubule-binding protein into mammalian cells to promote colonization
• Science, Volume 391, Issue 6787, Page 825-830, February 2026.
A flaw in using pretrained protein language models in protein-protein interaction inference models
• Abstract With the growing pervasiveness of pretrained protein language models (pLMs), pLM-based methods are increasingly being put forward for the protein-protein interaction (PP
What is a 'seesaw protein' that switches functions by changing shape?
• Inspired by the simple mechanism of a seesaw-when one side goes up, the other side goes down-researchers asked an intriguing question: Could a single molecule switch between two
Accurate predictions of disordered protein ensembles with STARLING
• Abstract Intrinsically disordered proteins and regions (collectively IDRs) are found across all kingdoms of life and have critical roles in virtually every eukaryotic cellular pr
A flaw in using pretrained protein language models in protein-protein interaction inference models
• Nature Machine Intelligence, Published online: 13 February 2026; doi:10.1038/s42256-025-01176-7 The usage of pretrained protein language models (pLMs) is rapidly growing. • Howev
Benchmark of 1.4 million checked protein structures could sharpen AI predictions
• University of Missouri researchers have released the world’s largest collection of protein models with quality assessment-a groundbreaking new resource that could accelerate drug
Trapping a single protein in a molecular cage: A new path to drug discovery for amyotrophic lateral sclerosis
• Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for scientists to study their individual units without altering th
Longer roots for drought? How an edited protein could reshape crop resilience
• What’s the key to growing resilient crops that can survive tough conditions? • Researchers at the University of Missouri are getting to the root of it-literally. • Researchers in
GPT-5 lowers the cost of cell-free protein synthesis
• An autonomous lab combining OpenAI’s GPT-5 with Ginkgo Bioworks’ cloud automation cut cell-free protein synthesis costs by 40% through closed-loop experimentation.
Repurposing Protein Folding Models for Generation with Latent Diffusion
• PLAID is a multimodal generative model that simultaneously generates protein 1D sequence and 3D structure, by learning the latent space of protein folding models. • The awarding