Machinery

Roles of microtubules and LIS1 in dynein transport machinery assembly

• Abstract Cytoplasmic dynein-1, a microtubule (MT)-based motor protein, requires dynactin and a coiled-coil adaptor to form the processive dynein-dynactin-adaptor (DDA) complex1,2

Giant DNA viruses encode their own eukaryote-like translation machinery, researchers discover

• In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. • The find