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A flaw in using pretrained protein language models in protein-protein interaction inference models

A flaw in using pretrained protein language models in protein-protein interaction inference models

• Abstract With the growing pervasiveness of pretrained protein language models (pLMs), pLM-based methods are increasingly being put forward for the protein-protein interaction (PP

Research & Labs · February 24, 2026 (updated February 24, 2026) · 2 min · 279 words
A flaw in using pretrained protein language models in protein-protein interaction inference models

A flaw in using pretrained protein language models in protein-protein interaction inference models

• Abstract With the growing pervasiveness of pretrained protein language models (pLMs), pLM-based methods are increasingly being put forward for the protein-protein interaction (PP

Research & Labs · February 22, 2026 (updated February 23, 2026) · 2 min · 280 words

A flaw in using pretrained protein language models in protein-protein interaction inference models

• Nature Machine Intelligence, Published online: 13 February 2026; doi:10.1038/s42256-025-01176-7 The usage of pretrained protein language models (pLMs) is rapidly growing. • Howev

Research · February 19, 2026 (updated February 19, 2026) · 1 min · 98 words