A membrane-bound nuclease directly cleaves phage DNA during genome injection

A membrane-bound nuclease directly cleaves phage DNA during genome injection

• Abstract From mammals to bacteria, the direct recognition and cleavage of viral nucleic acids is a potent defence strategy against viral infection, but it requires mechanisms for

Science · February 25, 2026 (updated February 25, 2026) · 2 min · 231 words
Convergent MurJ flippase inhibition by phage lysis proteins

Convergent MurJ flippase inhibition by phage lysis proteins

• Abstract Antimicrobial drug resistance poses a global health challenge that necessitates the identification of new druggable targets1,2,3 • The essential lipid II flippase MurJ i

Science · February 25, 2026 (updated February 25, 2026) · 1 min · 213 words