Convergent MurJ flippase inhibition by phage lysis proteins
• Abstract Antimicrobial drug resistance poses a global health challenge that necessitates the identification of new druggable targets1,2,3 • The essential lipid II flippase MurJ i
Inhibition
Nucleotide signals coordinate activation and inhibition of bacterial immunity
• Abstract The cellular nucleotide pool is a major focal point of the host immune response to viral infection. • Immune effector proteins that disrupt the nucleotide pool enable an