• Global cholera vaccine supply has now increased to a level sufficient to allow the resumption of life-saving preventive campaigns for the first time in over three years, Gavi, the Vaccine Alliance, UNICEF, and the World Health Organization (WHO) announced today. • Mozambique is the first country to restart preventive vaccination, following the halt in 2022 caused by the global surge in cholera cases that drove up demand and led to shortages of oral cholera vaccine (OCV) stocks. • The preventive vaccination campaign begins amid an ongoing cholera outbreak and the aftermath of floods that affected more than 700 000 people and displaced many. • The floods disrupted health systems and damaged water systems, further increasing the risk of waterborne diseases such as cholera. • “Global vaccine shortages forced us into a cycle of reacting to cholera outbreaks instead of preventing them. • We are now in a stronger position to break that cycle.

Article Summaries:

  • Global cholera vaccine supplies have now reached a level that allows the first preventive vaccination campaigns in more than three years. Gavi, UNICEF and WHO announced that 20 million oral cholera vaccine (OCV) doses will be deployed, with 3.6 million to Mozambique, 6.1 million to the Democratic Republic of the Congo and 10.3 million to Bangladesh. The increase follows a doubling of annual OCV production from 35 million doses in 2022 to nearly 70 million in 2025, largely enabled by the manufacturer EUBiologics. Mozambique’s campaign begins amid an ongoing outbreak and recent floods that disrupted water systems, underscoring the need for complementary water‑and‑sanitation improvements.

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