• The trigeminal nerve is implicated in migraine, so it represents a target for better treatmentsjitendra jadhav/Alamy The trigeminal nerve is implicated in migraine, so it represents a target for better treatments jitendra jadhav/Alamy We could be on the cusp of a new wave of migraine therapies. • Revisiting a neurological pathway that has long been dismissed for treating the painful condition has yielded promising results. • By understanding the various mechanisms behind migraine, whichaffects more than 1 billion people worldwide, we could provide relief for the 1 in 3 people with the condition who don’t respond to current treatments. • Failed drug trials over the past few decades meant many dismissed this pathway as inconsequential in our quest to prevent and treat migraine. • But now, a placebo-controlled study has some wondering if this may have been too hasty. • Read moreMost effective migraine drugs revealed by review of trial data Read more Most effective migraine drugs revealed by review of trial data Messoud Ashinaat the University of Copenhagen in Denmark and his colleagues have looked at a chemical messenger, or neuropeptide, called substance P.

Article Summaries:

  • We could be on the cusp of a new wave of migraine therapies. Revisiting a neurological pathway that has long been dismissed for treating the painful condition has yielded promising results. By understanding the various mechanisms behind migraine, which affects more than 1 billion people worldwide, we could provide relief for the 1 in 3 people with the condition who don’t respond to current treatments. Failed drug trials over the past few decades meant many dismissed this pathway as inconsequential in our quest to prevent and treat migraine. But now, a placebo-controlled study has some wonderin

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