• Illustration of CAR T-cell therapy (green) attacking a cancer cell (pink)NEMES LASZLO/SCIENCE PHOTO LIBRARY Illustration of CAR T-cell therapy (green) attacking a cancer cell (pink) NEMES LASZLO/SCIENCE PHOTO LIBRARY Genetically engineered immune cells known as CAR-T cells might be able to slow the progress of the neurodegenerative condition amyotrophic lateral sclerosis (ALS) by killing off rogue immune cells in the brain. • “It’s not a way to cure the disease,” saysDavide Trottiat the Jefferson Weinberg ALS Center in Pennsylvania. • “The goal is slowing down the disease.” Read moreCAR T-cell therapy makes ageing guts heal themselves Read more CAR T-cell therapy makes ageing guts heal themselves The life expectancy of people diagnosed with ALS is just two to five years, so slowing the condition’s progression would make a big difference, says Trotti. • It’s possible that the same approach could help slow other neurodegenerative conditions too. • Also known as Lou Gehrig’s disease, ALS is caused by the loss of motor neurons, the nerve cells that control voluntary muscles. • PhysicistStephen Hawkinghad ALS, but his case was exceptional because he lived so long.
Article Summaries:
- Genetically engineered immune cells known as CAR-T cells might be able to slow the progress of the neurodegenerative condition amyotrophic lateral sclerosis (ALS) by killing off rogue immune cells in the brain. “It’s not a way to cure the disease,” says Davide Trotti at the Jefferson Weinberg ALS Center in Pennsylvania. “The goal is slowing down the disease.” The life expectancy of people diagnosed with ALS is just two to five years, so slowing the condition’s progression would make a big difference, says Trotti. It’s possible that the same approach could help slow other neurodegenerative cond
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